Recombinant MS4A1 (Ibritumomab Biosimilar) antibody
This Mammalian Cells Monoclonal antibody specifically detects MS4A1 (Ibritumomab Biosimilar) in ELISA. It exhibits reactivity toward Human.
Catalog No. ABIN7488261
$323.13
Plus shipping costs $50.00
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United States
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Quick Overview for Recombinant MS4A1 (Ibritumomab Biosimilar) antibody (ABIN7488261)
Target
MS4A1 (Ibritumomab Biosimilar)
Antibody Type
Recombinant Antibody
Reactivity
Human
Host
Mammalian Cells
Clonality
Monoclonal
Conjugate
This MS4A1 (Ibritumomab Biosimilar) antibody is un-conjugated
Application
ELISA
Grade
Research Grade
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Expression System
- Mammalian cells
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Purpose
- Ibritumomab Biosimilar - Anti-MS4A1(CD20,MS4A-1) mAb
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Characteristics
- Antibody Type: Human IgG2A
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Purification
- Recombinant antibody expressed in mammalien cells and purified.
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Isotype
- IgG
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Restrictions
- For Research Use only
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Buffer
- PBS pH 7.5
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Storage
- -80 °C
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Storage Comment
- store at -80°C
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- MS4A1 (Ibritumomab Biosimilar)
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Target Type
- Biosimilar
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Background
- Ibritumomab is a monoclonal antibody directed against the CD20 antigen found on pre-B and mature B lymphocytes (normal and malignant). Ibritumomab binding induces apoptosis in B lymphocytes in vitro. It is combined with the chelator tiuxetan, which acts as a specific chelation site for Yttrium-90 (Y-90). The monoclonal antibody acts as a delivery system to direct the radioactive isotope to the targeted cells, however, binding has been observed in lymphoid cells throughout the body and in lymphoid nodules in organs such as the large and small intestines. beta-emission induces cellular damage through the formation of free radicals (in both target cells and surrounding cells).
Target
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