Recombinant antibody expressed in mammalien cells and purified.
Grade
Research Grade
Isotype
IgG2 lambda
Restrictions
For Research Use only
Buffer
PBS pH 7.5
Storage
-80 °C
Storage Comment
store at -80°C
Target
PCSK9 (Evolocumab Biosimilar)
Target Type
Biosimilar
Background
AMG 145,Anti-PCSK9 Evolocumab is a human IgG2 monoclonal antibody that binds to and prevents the binding of the proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a protein that binds to LDL receptors for degradation, thus reducing the liver’s activity of removal of LDL-cholesterol (LDL-C) from the blood. It is used in the treatment of hyperlipidemia.