CEP290 antibody (AA 2429-2479)

Catalog No. ABIN7448387

Product Details anti-CEP290 Antibody

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Binding Specificity: AA 2429-2479

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP290 antibody is un-conjugated

Application: Immunofluorescence (fixed cells) (IF/ICC)

Purpose: Rabbit anti-CEP290 IHC Antibody, affinity purified

Predicted Reactivity: Horse,Orangutan,Monkey,Gorilla,Northern white-cheeked gibbon,Small-eared galago,African elephant

Purification: Affinity Purified

Immunogen: Between AA 2429 and 2479

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 500 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Alternative Name: CEP290 (CEP290 Products)

Background: Background: Centrosomal protein 290 (CEP290) is a member of the nephrocystins, a family of proteins involved in renal cystic diseases. CEP290 and the nephrocystins appear to play a role in cilia and basal body function. Loss-of-function mutations in CEP290 result in Joubert syndrome and related disorders characterized by brain malformations, developmental delay, ataxia, irregular breathing, renal disease, and hepatic fibrosis.

Gene ID: 80184

NCBI Accession: NP_079390

UniProt: O15078

Pathways: cAMP Metabolic Process, M Phase