DDIT4 antibody (AA 1-50)

Catalog No. ABIN7448394

The Rabbit Polyclonal anti-DDIT4 antibody (ABIN7448394) specifically detects DDIT4 in IF/ICC. The antibody is reactive with Human samples.

Quick Overview for DDIT4 antibody (AA 1-50) (ABIN7448394)

Target: DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDIT4 antibody is un-conjugated

Application: Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-DDIT4 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-REDD1 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine,Dog,Horse,Rabbit,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Little brown bat,Crab-eating macaque,Chinese hamster,African elephant,White-tufted-ear marmoset

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DDIT4

Target: DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))

Alternative Name: REDD1

Background: Background: REDD1 (regulated in development and DNA damage response 1) is a direct transcriptional target of HIF. It plays a role in the TSC/mTOR pathway as a regulator upstream of the TSC1/2 complex. In response to both hypoxia and energy stress, REDD1 inhibits mTOR activity in a TSC-dependent manner. Alternative names for REDD1 include DDIT4, DNA-damage-inducible transcript 4 protein, and RTP801.

Gene ID: 54541

NCBI Accession: NP_061931

UniProt: Q9NX09

Pathways: Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process