beta Catenin antibody (AA 760-781)

Catalog No. ABIN7448432

The Rabbit Polyclonal anti-beta Catenin antibody has been validated for IHC. It is suitable to detect beta Catenin in samples from Human and Mouse.

Quick Overview for beta Catenin antibody (AA 760-781) (ABIN7448432)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Catenin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-beta Catenin Antibody

Binding Specificity: AA 760-781

Purpose: Rabbit anti-beta atenin IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Pipidae,Chinese hamster,Medaka fish,Mongolian jird,Bird,White-tufted-ear marmoset,Tasmanian devil,Duckbill platypus,Atlantic salmon,Domestic duck,Crab-eating macaque,Small-eared galago,Chinese softshell turtle,Little brown bat,Thirteen-lined ground squirrel,African elephant,Japanese pufferfish,Naked mole rat,Spotted green pufferfish,Gray short-tailed opossum,Nile tilapia,Goldfish,West Indian ocean coelacanth,Northern white-cheeked gibbon,Zebra finch,Green anole,Three-spined stickleback

Purification: Affinity Purified

Immunogen: Between AA 760 and 781

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Alternative Name: beta Catenin

Background: Background: beta Catenin plays an integral role in the Wnt signaling pathway and is critical to morphogenic signaling and body axis specification. Beta Catenin exists in complexes with cadherins, transmembrane proteins that mediate cell adhesion. When Wnt-signaling proteins bind their receptors, beta Catenin is stabilized and accumulates in the cell. Translocation of stabilized beta Catenin allows its association with transcription factors and the activation of specific gene expression.

Gene ID: 1499

NCBI Accession: NP_001895

UniProt: P35222

Pathways: Peptide Hormone Metabolism