BUB3 antibody (AA 275-325)

Catalog No. ABIN7448449

This Rabbit Polyclonal antibody specifically detects BUB3 in IHC. It exhibits reactivity toward Human.

Quick Overview for BUB3 antibody (AA 275-325) (ABIN7448449)

Target: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BUB3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-BUB3 Antibody

Binding Specificity: AA 275-325

Purpose: Rabbit anti-Bub3 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Crab-eating macaque,Tasmanian devil,White-tufted-ear marmoset,Naked mole rat,Gray short-tailed opossum,Small-eared galago,Thirteen-lined ground squirrel,African elephant,Little brown bat,Chinese hamster

Purification: Affinity Purified

Immunogen: Between AA 275 and 325

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BUB3

Target: BUB3 (Budding Uninhibited By Benzimidazoles 3 Homolog (Yeast) (BUB3))

Alternative Name: Bub3

Background: Background: Bub3 is an adaptor protein and component of the spindle checkpoint machinery. Bub3 and other spindle checkpoint proteins ensure that segregation does not proceed until all replicated chromatids are associated with a functional bipolar spindle. Bub3 forms a constitutive complex with Bub1. Bub3 has been demonstrated to also function as a transcriptional repressor in association with Cdc20 and histone deacetylases.

Gene ID: 9184

NCBI Accession: NP_004716

UniProt: O43684

Pathways: Maintenance of Protein Location