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CBP antibody (AA 2375-2425)

The Rabbit Polyclonal anti-CBP antibody has been validated for IHC. It is suitable to detect CBP in samples from Human.
Catalog No. ABIN7448459

Quick Overview for CBP antibody (AA 2375-2425) (ABIN7448459)

Target

See all CBP (CREBBP) Antibodies
CBP (CREBBP) (CREB Binding Protein (CREBBP))

Reactivity

  • 83
  • 42
  • 38
  • 3
  • 3
  • 3
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  • 2
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  • 1
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Human

Host

  • 82
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Rabbit

Clonality

  • 81
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Polyclonal

Conjugate

  • 47
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
This CBP antibody is un-conjugated

Application

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  • 15
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  • 3
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Immunohistochemistry (IHC)
  • Binding Specificity

    • 10
    • 8
    • 5
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    • 2
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    • 1
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    AA 2375-2425

    Purpose

    Rabbit anti-CBP IHC Antibody, Affinity Purified

    Predicted Reactivity

    Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Small-eared galago,White-tufted-ear marmoset

    Purification

    Affinity Purified

    Immunogen

    Between AA 2375 and 2425

    Isotype

    IgG
  • Application Notes

    1:100 - 1:500

    Restrictions

    For Research Use only
  • Concentration

    500 μg/mL

    Buffer

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    CBP (CREBBP) (CREB Binding Protein (CREBBP))

    Alternative Name

    CBP

    Background

    Background: CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.

    Gene ID

    1387

    NCBI Accession

    NP_004371

    UniProt

    Q92793

    Pathways

    TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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