CBP antibody (AA 2375-2425)
Quick Overview for CBP antibody (AA 2375-2425) (ABIN7448459)
Target
See all CBP (CREBBP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 2375-2425
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Purpose
- Rabbit anti-CBP IHC Antibody, Affinity Purified
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Predicted Reactivity
- Orangutan,Monkey,Gorilla,Chimpanzee,Northern white-cheeked gibbon,Small-eared galago,White-tufted-ear marmoset
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Purification
- Affinity Purified
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Immunogen
- Between AA 2375 and 2425
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Isotype
- IgG
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Application Notes
- 1:100 - 1:500
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Restrictions
- For Research Use only
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Concentration
- 500 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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Alternative Name
- CBP
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Background
- Background: CBP [cAMP response element-binding protein (CREB)-binding protein] interacts with and is a transcriptional co-activator of a multitude of transcriptional regulators that includes CREB. CBP is structurally and functionally similar to p300 but is encoded by an independent gene. CBP coactivation may be achieved through the regulation of chromatin structure due to its ability to catalyze the acetylation of histones. CBP has potential tumor suppressor properties and is important to integrating cell-signaling cues for proliferation, differentiation and apoptosis.
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Gene ID
- 1387
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NCBI Accession
- NP_004371
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UniProt
- Q92793
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Pathways
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
Target
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