CDK2 antibody (AA 248-298)

Catalog No. ABIN7448471

The Rabbit Polyclonal anti-CDK2 antibody has been validated for IHC. It is suitable to detect CDK2 in samples from Human and Mouse.

Quick Overview for CDK2 antibody (AA 248-298) (ABIN7448471)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CDK2 Antibody

Binding Specificity: AA 248-298

Purpose: Rabbit anti-CDK2 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Sheep,Goat,Bovine,Dog,Horse,Rabbit,Pig,Golden hamster,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Black rat,Small-eared galago,Northern white-cheeked gibbon,Chinese hamster,Thirteen-lined ground squirrel,White-tufted-ear marmoset,Little brown bat,Crab-eating macaque

Purification: Affinity Purified

Immunogen: Between AA 248 and 298

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: CDK2

Background: Background: Cyclin-dependent kinase 2 (CDK2) is a member of the CDK family of protein kinases that regulate cell cycle progression. CDK2 associates with cyclin E or cyclin A to drive the cell cycle through G1- and S-phase. Substrates of CDK2 include pRb, p53, p27, E2F, Brca1, CDK7, B-Myb, PP1 alpha, RNA Pol II CTD, axin, p220 NPAT, ribonucleotide reductase M2, Myo-D, MARCKS, HsCdc6, and CP110.

Gene ID: 1017

NCBI Accession: NP_001789

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA