CHD3 antibody (AA 1950-2000)

Catalog No. ABIN7448475

The Rabbit Polyclonal anti-CHD3 antibody (ABIN7448475) specifically detects CHD3 in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for CHD3 antibody (AA 1950-2000) (ABIN7448475)

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CHD3 Antibody

Binding Specificity: AA 1950-2000

Purpose: Rabbit anti-CHD3 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,Naked mole rat,Little brown bat,Chinese hamster,Tasmanian devil,Gray short-tailed opossum,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 1950 and 2000

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CHD3

Target: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Alternative Name: CHD3

Background: Background: CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes.

Gene ID: 1107

NCBI Accession: NP_001005273

UniProt: Q12873