This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Expiry Date
12 months
Target
CSNK2A1/CK II alpha (CSNK2A1)
(Casein Kinase 2 alpha 1 (CSNK2A1))
Alternative Name
CKII alpha
Background
Background: Casein kinase II (CKII) is a serine/threonine protein kinase that is required for progression through the cell cycle but whose major functions are not clearly understood. CKII is composed of a heterotetrameric complex that includes alpha and alpha-prime catalytic subunits and a beta non-catalytic subunit. Although from independent genes, CKII alpha and CKII alpha-prime can compensate for each other for some functions. However in response to ionizing radiation (IR) damage, CKII alpha and CKII alpha-prime appear to function independently in inhibiting apoptosis signaling.