Cullin 2 antibody (AA 150-200)

Catalog No. ABIN7448503

This Rabbit Polyclonal antibody specifically detects Cullin 2 in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for Cullin 2 antibody (AA 150-200) (ABIN7448503)

Target: Cullin 2 (CUL2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Cullin 2 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-Cul2 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,African elephant,Naked mole rat,Chinese hamster,Northern white-cheeked gibbon,Small-eared galago,White-tufted-ear marmoset,Thirteen-lined ground squirrel,Little brown bat

Purification: Affinity Purified

Immunogen: Between AA 150 and 200

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Cullin 2

Target: Cullin 2 (CUL2)

Alternative Name: Cul2

Background: Background: Cullin-2 (Cul2) is a core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. Cul2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme [taken from the Universal Protein Resource (UniProt) Q13617].

Gene ID: 8453

NCBI Accession: NP_003582

UniProt: Q13617

Pathways: M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome