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DDB1 antibody (C-Term)

This anti-DDB1 antibody is a Rabbit Polyclonal antibody detecting DDB1 in IHC. Suitable for Human and Mouse.
Catalog No. ABIN7448511

Quick Overview for DDB1 antibody (C-Term) (ABIN7448511)

Target

See all DDB1 Antibodies
DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

Reactivity

  • 45
  • 23
  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 37
  • 7
  • 1
Rabbit

Clonality

  • 35
  • 10
Polyclonal

Conjugate

  • 34
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DDB1 antibody is un-conjugated

Application

  • 31
  • 15
  • 15
  • 14
  • 11
  • 10
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • Binding Specificity

    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Purpose

    Rabbit anti-DDB1 IHC Antibody, Affinity Purified

    Predicted Reactivity

    Rat,X. laevis,X. tropicalis,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Chinese hamster,Small-eared galago,Gray short-tailed opossum,Green monkey,Thirteen-lined ground squirrel,Northern white-cheeked gibbon,Naked mole rat,African elephant,White-tufted-ear marmoset,Tasmanian devil,Little brown bat

    Purification

    Affinity Purified

    Immunogen

    Between AA 1100 and C-term

    Isotype

    IgG
  • Application Notes

    1:100 - 1:500

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Expiry Date

    12 months
  • Target

    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))

    Alternative Name

    DDB1

    Background

    Background: DDB1 (DNA Damage Binding Protein 1) is a subunit of the DNA damage-binding protein complex (DDB) involved in DNA repair. As part of a complex with Cul4-based ubiquitin ligase, Cul4-Ddb1 can directly modify chromatin through the ubiquitination of histones as well as ubiquitinate other chromatin bound factors. A deficiency in Cul4-Ddb1 ubiquitin ligase has been associated with xeroderma pigmentosum, a heritable disease characterized by defects in nucleotide excision repair and skin cancer development.

    Gene ID

    1642

    UniProt

    Q16531, Q13289

    Pathways

    DNA Damage Repair
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