DDX17 antibody (C-Term)
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- Target See all DDX17 Antibodies
- DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DDX17 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purpose
- Rabbit anti-DDX17 IHC Antibody, Affinity Purified
- Predicted Reactivity
- Dog,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Crab-eating macaque,Little brown bat,Northern white-cheeked gibbon
- Purification
- Affinity Purified
- Immunogen
- Between AA 550 and C-term
- Isotype
- IgG
- Top Product
- Discover our top product DDX17 Primary Antibody
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- Application Notes
- 1:100 - 1:500
- Restrictions
- For Research Use only
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- Concentration
- 100 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))
- Alternative Name
- DDX17 (DDX17 Products)
- Background
- Background: DDX17 is a member of the DEAD box family of proteins that possesses several conserved motifs which include the highly conserved DEAD (Asp-Glu-Ala-Asp) amino acid sequence motif. The major activity of DEAD box proteins is to function as ATP-dependent RNA helicases. As helicases, DEAD proteins play an important role in all aspects of RNA metabolism and function which include pre-mRNA splicing, RNA synthesis, RNA degradation, RNA export, RNA translation, RNA secondary structure formation, ribosome biogenesis, and the assembly of RNP complexes. Some members of the DEAD box proteins also exhibit functions involved in transcriptional regulation. In addition to a role involved in RNA splicing, DDX17 has been observed to interact with and act as a transcriptional coactivator for estrogen receptor alpha (ERalpha). DDX17 is closely related to and forms heterodimers with DDX5.
- Gene ID
- 10521
- UniProt
- Q92841
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Muscle Cell Differentiation
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