GTF2IRD/TFII-IRD1 (AA 650-700) antibody

Catalog No. ABIN7448584

This Rabbit Polyclonal antibody specifically detects GTF2IRD/TFII-IRD1 in IHC. It exhibits reactivity toward Human.

Quick Overview for GTF2IRD/TFII-IRD1 (AA 650-700) antibody (ABIN7448584)

Target: GTF2IRD/TFII-IRD1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 650-700

Purpose: Rabbit anti-GTF2IRD/TFII-IRD1 IHC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Dog,Horse,Pig,Panda,Orangutan,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 650 and 700

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: GTF2IRD/TFII-IRD1

Background: Background: GTF2IRD1/TFII-IRD1 possesses five helix-loop-helix GTF2I-like repeats and has been shown to bind the GUCE (GTF2IRD1 upstream response element) regulatory motif found in HOXC8, GOOSECOID, and TROPONININ (SLOW) genes. GTF2IRD1/TFII-IRD1 may be involved in skeletal muscle differentiation and myogenesis. Haploinsufficiency of GTF2IRD1/TFII-IRD1 results in Williams-Beuren syndrome (WBS), a rare developmental disorder characterized by musculo-skeletal and cardiac abnormalities.

Gene ID: 9569

NCBI Accession: NP_057412

UniProt: Q9UHL9