hPrp3p (AA 100-150) antibody

Catalog No. ABIN7448600

The Rabbit Polyclonal anti-hPrp3p antibody is suitable to detect hPrp3p in samples from Human and Mouse. It has been validated for IHC.

Quick Overview for hPrp3p (AA 100-150) antibody (ABIN7448600)

Target: hPrp3p

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC)

Product Details

Binding Specificity: AA 100-150

Purpose: Rabbit anti-hPrp3p IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Chicken,Turkey,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,African elephant,Ferret,Crab-eating macaque,Tasmanian devil,Naked mole rat,Green anole,Chinese hamster,Northern white-cheeked gibbon,Little brown bat,Gray short-tailed opossum,Small-eared galago,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogen: Between AA 100 and 150

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details

Target: hPrp3p

Background: Background: hPrp3p (human pre-mRNA splicing factor 3) was identified as a factor that associated with U4/U6 snRNPs which are components of the splicesome. hPrp3p is homologous to S. cerevisiae splicing factor Prp3p. Mutations in the PRPF3 gene are associated with retinitis pigmentosa-18. It has been determined that mutations in hPrp3p may alter the recognition motif for phosphorylation by casein kinase II (CKII) and that loss of phosphorylation may result in aberrant interactions within the U4/U6 snRNP complex.

Gene ID: 9129

NCBI Accession: NP_004689

UniProt: O43395