Tumor Protein p73 antibody (AA 1-62)

Catalog No. ABIN7448710

This Rabbit Polyclonal antibody specifically detects Tumor Protein p73 in IHC. It exhibits reactivity toward Human.

Quick Overview for Tumor Protein p73 antibody (AA 1-62) (ABIN7448710)

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tumor Protein p73 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Tumor Protein p73 Antibody

Binding Specificity: AA 1-62

Purpose: Rabbit anti-p73 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,Small-eared galago,Green monkey

Purification: Affinity Purified

Immunogen: Between AA 1 and 62

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Tumor Protein p73

Target: Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))

Alternative Name: p73

Background: Background: p73 is a p53-related protein and a member of the family of transcription factors which include p53, p63 and p73. Although structurally and functionally related, it appears that the members of this family possess their own unique functions. No human genetic disorders have been linked to germ line mutations of p73, however, loss of heterozygosity has been associated with some cancers although the incidence is rare. Generally speaking, p73 appears to play an important role in gene transactivation and growth suppression. P73 participates in the apoptotic response to DNA damage and may function in connection with p53.

Gene ID: 7161

NCBI Accession: NP_005418

UniProt: O15350

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus