Paxillin antibody (AA 1-50)

Catalog No. ABIN7448716

This Rabbit Polyclonal antibody specifically detects Paxillin in IHC. It exhibits reactivity toward Human.

Quick Overview for Paxillin antibody (AA 1-50) (ABIN7448716)

Target: Paxillin (PXN)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paxillin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-Paxillin Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-Paxillin IHC Antibody, Affinity Purified

Predicted Reactivity: Bovine,Dog,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,White-tufted-ear marmoset,Small-eared galago,Little brown bat,African elephant,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Paxillin

Target: Paxillin (PXN)

Alternative Name: Paxillin

Background: Background: Paxillin functions as a signal transduction adaptor protein that localizes to focal adhesions and is involved in cell-adhesion and motility. Paxillin is a substrate of several protein kinases such as Src, FAK, and JNK. Serine and threonine phosphorylation of Paxillin appears to dictate its specific cellular activities.

Gene ID: 5829

NCBI Accession: NP_001074324

UniProt: P49023

Pathways: MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling