PRMT5 antibody (C-Term)

Catalog No. ABIN7448743

This Rabbit Polyclonal antibody specifically detects PRMT5 in IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for PRMT5 antibody (C-Term) (ABIN7448743)

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT5 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-PRMT5 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-PRMT5 IHC Antibody, Affinity Purified

Predicted Reactivity: X. laevis,X. tropicalis,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Duckbill platypus,Little brown bat,Naked mole rat,Northern white-cheeked gibbon,African elephant,Gray short-tailed opossum,Crab-eating macaque,Small-eared galago,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogen: Between AA 580 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PRMT5

Target: PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))

Alternative Name: PRMT5

Background: Background: Protein arginine methylation is a form of post-translational modification that is catalyzed by protein arginine methyltransferases (PRMTs). PRMT5 interacts with the SWI/SNF complexes and methylates histones H3 and H4. This finding suggests that PRMT5 is involved in the structural modification of chromatin and the regulation of gene transcription.

Gene ID: 10419

NCBI Accession: NP_006100

UniProt: O14744

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development