RANGAP1 antibody (AA 400-450)

Catalog No. ABIN7448754

The Rabbit Polyclonal anti-RANGAP1 antibody (ABIN7448754) specifically detects RANGAP1 in IHC. The antibody is reactive with Human samples.

Quick Overview for RANGAP1 antibody (AA 400-450) (ABIN7448754)

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANGAP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-RANGAP1 Antibody

Binding Specificity: AA 400-450

Purpose: Rabbit anti-RanGAP1 IHC Antibody, Affinity Purified

Predicted Reactivity: Orangutan,Chimpanzee,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 400 and 450

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RANGAP1

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Alternative Name: RanGAP1

Background: Background: The regulation of GTPase activity is achieved via activators called GEFs (guanine-nucleotide exchange factors) and inactivators called GAPs (GTPase-activating proteins). Ran-specific GTPase-activating protein 1 (RanGAP1) induces the GTPase activity of the RAN small GTPase. The Ran GTPase plays a role in spatial information and nucleocytoplasmic transport. RanGAP1 is the antagonist of the GEF RCC1 which keeps RAN in the active GTP-bound state.

Gene ID: 5905

NCBI Accession: NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus