SMC1A antibody (C-Term)

Catalog No. ABIN7448802

The Rabbit Polyclonal anti-SMC1A antibody (ABIN7448802) specifically detects SMC1A in IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for SMC1A antibody (C-Term) (ABIN7448802)

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC1A antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-SMC1A Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-SMC1 IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,X. laevis,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Northern white-cheeked gibbon,Little brown bat,White-tufted-ear marmoset,African elephant,Chinese hamster,Duckbill platypus,Naked mole rat,Crab-eating macaque,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 1175 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SMC1A

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Alternative Name: SMC1

Background: Background: Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.

Gene ID: 8243

NCBI Accession: NP_006297

UniProt: Q14683

Pathways: Stem Cell Maintenance