VCP antibody (C-Term)

Catalog No. ABIN7448858

The Rabbit Polyclonal anti-VCP antibody is suitable to detect VCP in samples from Human and Mouse. It has been validated for IHC.

Quick Overview for VCP antibody (C-Term) (ABIN7448858)

Target: VCP (Valosin Containing Protein (VCP))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VCP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-VCP Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-VCP IHC Antibody, Affinity Purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Ferret,Crab-eating macaque,Chinese hamster,Naked mole rat,Little brown bat,Northern white-cheeked gibbon,Gray short-tailed opossum,White-tufted-ear marmoset,Tasmanian devil,Thirteen-lined ground squirrel,Small-eared galago

Purification: Affinity Purified

Immunogen: Between AA 750 and C-term

Isotype: IgG

Application Details

Application Notes: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for VCP

Target: VCP (Valosin Containing Protein (VCP))

Alternative Name: VCP

Background: Background: Valosin-containing protein (VCP) is a multifunctional protein that is proposed to be involved in vesicle transport and fusion for protein trafficking, 26S proteasome function in ubiquitin-based degradation pathways, and the assembly of peroxisomes. Mutations in the human VCP gene have been associated with diseases such as inclusion body myopathy, Paget disease of the bone, and frontotemporal dementia (IBMPFD). VCP can inhibit apoptosis and may play a role in tumorigenesis.

Gene ID: 7415

NCBI Accession: NP_009057

UniProt: P55072

Pathways: ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Ubiquitin Proteasome Pathway