RAPGEF2 antibody (AA 975-1025)

Catalog No. ABIN7448889

This anti-RAPGEF2 antibody is a Rabbit Polyclonal antibody detecting RAPGEF2 in IHC. Suitable for Human.

Quick Overview for RAPGEF2 antibody (AA 975-1025) (ABIN7448889)

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-RAPGEF2 Antibody

Binding Specificity: AA 975-1025

Purpose: Rabbit anti-PDZ-GEF1 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Monkey,Gorilla,Chimpanzee,Crab-eating macaque,White-tufted-ear marmoset,African elephant,Chinese hamster,Thirteen-lined ground squirrel,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 975 and 1025

Isotype: IgG

Application Details

Application Notes: 1:100 to 1:500. Epitope retrieval with citrate Buffer pH 6.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RAPGEF2

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Alternative Name: PDZ-GEF1

Background: Background: PDZ-GEF1 is a guanine nucleotide exchange factor (GEF) for Rap GTPases. It contains one PDZ-signaling domain, a Ras-association (RA) domain, and a region related to a cyclic nucleotide binding domain (RCBD). PDZ-GEF1 functions to catalyze the exchange of GDP for GTP and activate Rap1A, Rap1B, and Rap2B GTPase activity.

Gene ID: 9693

NCBI Accession: NP_055062

UniProt: Q9Y4G8

Pathways: Neurotrophin Signaling Pathway