Recombinant PD-1 antibody (AA 24-164)

Catalog No. ABIN7448892

The Rabbit Monoclonal anti-PD-1 antibody (Clone BLR076G) (ABIN7448892) specifically detects PD-1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant PD-1 antibody (AA 24-164) (ABIN7448892)

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PD-1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: BLR076G

Product Details anti-PD-1 Antibody

Binding Specificity: AA 24-164

Purpose: Rabbit anti-PD-1 Recombinant Monoclonal Antibody [BLR076G]

Purification: Purified

Immunogen: residues 24-164 (ECD)

Isotype: IgG

Application Details

Application Notes: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for PD-1

Target: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Alternative Name: PD-1

Background: PD-1 is a cell surface membrane protein of the immunoglobulin superfamily. It is an inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. PD-1 delivers inhibitory signals upon binding to ligands CD274/PD-L1 and CD273/PD-L2. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15116].

Gene ID: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints