KAP1 antibody (AA 1-50)

Catalog No. ABIN7448920

This Rabbit Polyclonal antibody specifically detects KAP1 in IHC and IF/ICC. It exhibits reactivity toward Human.

Quick Overview for KAP1 antibody (AA 1-50) (ABIN7448920)

Target: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KAP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-KAP1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-KAP-1 IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Bovine,Dog,Horse,Rabbit,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,Chinese hamster,Northern white-cheeked gibbon,White-tufted-ear marmoset,Crab-eating macaque,Nine-banded armadillo,Small-eared galago,Olive baboon,Thirteen-lined ground squirrel

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

ICC-IF: 1:100 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for KAP1

Target: KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

Alternative Name: KAP-1

Background: Background: KAP-1 (KRAB-Associated Protein 1) is a member of the tripartite motif RBCC/Trim domain family that contains a RING finger domain, B boxes, and an alpha helical coiled coil region. KAP-1 functions as a corepressor by interacting with the KRAB domain of KRAB zinc-finger transcriptional repressors. KAP-1 also appears to function as a scaffold for chromatin-remodeling complexes involved in transcriptional repression.

Gene ID: 10155

NCBI Accession: NP_005753

UniProt: Q13263

Pathways: Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus