CNOT3 antibody (AA 525-575)

Catalog No. ABIN7448941

This Rabbit Polyclonal antibody specifically detects CNOT3 in IHC and IF (p). It exhibits reactivity toward Human.

Quick Overview for CNOT3 antibody (AA 525-575) (ABIN7448941)

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CNOT3 Antibody

Binding Specificity: AA 525-575

Purpose: Rabbit anti-CNOT3 IHC Antibody, Affinity Purified

Predicted Reactivity: Dog,Orangutan,Monkey,Gorilla,Chimpanzee,Nine-banded armadillo,Crab-eating macaque,Greater horseshoe bat,Gray short-tailed opossum,Small-eared galago,Olive baboon

Purification: Affinity Purified

Immunogen: Between AA 525 and 575

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CNOT3

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Alternative Name: CNOT3

Background: Background: CNOT3 (CCR4-NOT transcription complex subunit 3) is a component of the CCR4-NOT core complex that functions as a general transcriptional regulator. In a genome-wide siRNA screen for genes essential for mouse embryonic stem cell self-renewal, CNOT3 was identified and found to co-occupy gene promoters with c-Myc and Zfx.

Gene ID: 4849

NCBI Accession: NP_055331

UniProt: O75175

Pathways: Stem Cell Maintenance