PTPN12 antibody (AA 760-780)

Catalog No. ABIN7449005

The Rabbit Polyclonal anti-PTPN12 antibody is suitable to detect PTPN12 in samples from Human and Mouse. It has been validated for IHC and IF (p).

Quick Overview for PTPN12 antibody (AA 760-780) (ABIN7449005)

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN12 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PTPN12 Antibody

Binding Specificity: AA 760-780

Purpose: Rabbit anti-PTPN12 IHC Antibody, affinity purified

Predicted Reactivity: Rat,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,West Indian ocean coelacanth,Tasmanian devil,Crab-eating macaque,White-tufted-ear marmoset,Thirteen-lined ground squirrel,African elephant,Gray short-tailed opossum,Naked mole rat,Chinese hamster,Northern white-cheeked gibbon,Duckbill platypus

Purification: Affinity Purified

Immunogen: Between AA 760 and 780

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 250 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PTPN12

Target: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Alternative Name: PTPN12

Background: Background: PTPN12 is a cytosolic protein tyrosine phosphatase (PTP) that contains a C-terminal PEST motif and plays an important role in cytoskeletal organization, immune cell activation, apoptosis, and embryonic development. PTPN12 appears to contribute to these cellular processes through its interaction with a variety of signaling and cytoskeletal-associated proteins. The recent discovery that PTPN12 is modulated by caspase-3 cleavage has led to the analysis of the role of PTPN12 and other PTPs as regulators of apoptosis.

Gene ID: 5782

NCBI Accession: NP_002826

UniProt: Q05209