RAD23B antibody (AA 359-409)

Catalog No. ABIN7449006

This anti-RAD23B antibody is a Rabbit Polyclonal antibody detecting RAD23B in IHC and IF (p). Suitable for Human.

Quick Overview for RAD23B antibody (AA 359-409) (ABIN7449006)

Target: RAD23B (RAD23 Homolog B (RAD23B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD23B antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-RAD23B Antibody

Binding Specificity: AA 359-409

Purpose: Rabbit anti-RAD23B IHC Antibody, Affinity Purified

Predicted Reactivity: Mouse,Rat,Chicken,Bovine,Dog,Horse,Rabbit,Guinea pig_10141,Pig,Panda,Orangutan,Monkey,Gorilla,Chimpanzee,African elephant,Tasmanian devil,White-tufted-ear marmoset,Duckbill platypus,Thirteen-lined ground squirrel,Little brown bat,Green anole,Small-eared galago,Naked mole rat,Gray short-tailed opossum,Nile tilapia,Crab-eating macaque,Zebra finch,Northern white-cheeked gibbon

Purification: Affinity Purified

Immunogen: Between AA 359 and 409

Isotype: IgG

Application Details

Application Notes:

IHC-IF: 1:50 - 1:500

IHC: 1:100 - 1:500

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Alternative Name: RAD23B

Background: Background: RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23B was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Gene ID: 5887

NCBI Accession: NP_002865

UniProt: P54727

Pathways: DNA Damage Repair