LZTFL1 antibody (AA 150-200)

Catalog No. ABIN7449196

This Rabbit Polyclonal antibody specifically detects LZTFL1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for LZTFL1 antibody (AA 150-200) (ABIN7449196)

Target: LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTFL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LZTFL1 Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-LZTFL1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 150 and 200

Isotype: IgG

Application Details

Application Notes: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LZTFL1

Target: LZTFL1 (Leucine Zipper Transcription Factor-Like 1 (LZTFL1))

Alternative Name: LZTFL1

Background: Background: LZTFL1 is a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in its gene cause a form of Bardet-Biedl Syndrome, a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This protein may also function as a tumor suppressor, possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. [provided by RefSeq, Feb 2013] [taken from NCBI Entrez Gene (Gene ID: 54585)].

Gene ID: 54585

UniProt: Q9NQ48