RNF213 antibody (AA 4300-4350)
Quick Overview for RNF213 antibody (AA 4300-4350) (ABIN7449254)
Target
See all RNF213 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 4300-4350
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Purpose
- Rabbit anti-RNF213 Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 4300 and 4350
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Isotype
- IgG
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Application Notes
- 1:2,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 1000 μg/mL
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Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- RNF213 (Ring Finger Protein 213 (RNF213))
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Alternative Name
- RNF213
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Background
- Background: RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity. [taken from the Universal Protein Resource (UniProt) Q63HN8].
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Gene ID
- 57674
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UniProt
- Q63HN8
Target
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