PAFAH1B1 antibody (AA 1-50)

Catalog No. ABIN7449274

This Rabbit Polyclonal antibody specifically detects PAFAH1B1 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PAFAH1B1 antibody (AA 1-50) (ABIN7449274)

Target: PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAFAH1B1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAFAH1B1 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-LIS-1 Antibody, Affinity Purified

Predicted Reactivity: Zebrafish,X. laevis,X. tropicalis,Chicken,Bovine,Pig,Cat,Orangutan,Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 1 and 50

Isotype: IgG

Application Details

Application Notes: 1:500 - 1:2,500

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PAFAH1B1

Target: PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))

Alternative Name: LIS-1

Background: Background: Lissencephaly-1 protein (LIS-1) was identified as a gene associated with Miller-Dieker lissencephaly syndrome, an autosomal dominant disorder characterized by microcephaly along with anomalies of the kidney, heart, and gastrointestinal tract. LIS-1 is the non-catalytic alpha subunit of the intracellular isoform of platelet-activating factor acetylhydrolase. LIS-1 plays an important role in neuron migration during brain development and fibroblast migration during wound healing. Its role in migration is related to its function in regulating dynein-mediated microtubule sliding.

Gene ID: 5048

NCBI Accession: NP_000421

UniProt: P43034

Pathways: M Phase, Regulation of Cell Size