SMC4 antibody (AA 600-650)

Catalog No. ABIN7449361

This Rabbit Polyclonal antibody specifically detects SMC4 in WB and IF/ICC. It exhibits reactivity toward Human.

Quick Overview for SMC4 antibody (AA 600-650) (ABIN7449361)

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Product Details anti-SMC4 Antibody

Binding Specificity: AA 600-650

Purpose: Rabbit anti-SMC4 Antibody, Affinity Purified

Predicted Reactivity: Mouse

Purification: Affinity Purified

Immunogen: between AA 600 and 650

Isotype: IgG

Application Details

Application Notes:

ICC-IF: 1:500 - 1:2,000

WB: 1:1,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for SMC4

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Alternative Name: SMC4

Background: Background: SMC (Structural maintenance of chromosomes) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core condensin complex includes a heterodimer of SMC2 and SMC4 that functions to create positively supercoiled loops for chromatin condensation and metaphase chromatid shaping. A function for condensin in the DNA damage checkpoint response and gene repression has also been suggested.

Gene ID: 10051

NCBI Accession: NP_005487

UniProt: Q9NTJ3