IRF3 antibody (AA 100-150)

Catalog No. ABIN7449377

The Rabbit Polyclonal anti-IRF3 antibody has been validated for WB and IHC. It is suitable to detect IRF3 in samples from Human.

Quick Overview for IRF3 antibody (AA 100-150) (ABIN7449377)

Target: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-IRF3 Antibody

Binding Specificity: AA 100-150

Purpose: Rabbit anti-IRF3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 100 and 150

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for IRF3

Target: IRF3 (Interferon Regulatory Factor 3 (IRF3))

Alternative Name: IRF3

Background: Background: Interferon regulatory factor 3 (IRF3) is a member of the IRF family of transcription factors that plays a critical role in immune cell function and development. IRF3 mediates interferon-stimulated response element (ISRE) promoter activation and functions as a molecular switch for antiviral activity.

Gene ID: 3661

NCBI Accession: NP_001562

UniProt: Q14653

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades