BOP1 antibody (AA 350-400)

Catalog No. ABIN7449379

This Rabbit Polyclonal antibody specifically detects BOP1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for BOP1 antibody (AA 350-400) (ABIN7449379)

Target: BOP1 (Block of Proliferation 1 (BOP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-BOP1 Antibody

Binding Specificity: AA 350-400

Purpose: Rabbit anti-BOP1 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: between AA 350 and 400

Isotype: IgG

Application Details

Application Notes:

IHC: 1:200 to 1:1000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for BOP1

Target: BOP1 (Block of Proliferation 1 (BOP1))

Alternative Name: BOP1

Background: Background: BOP1 (block of proliferation 1) is a component of the PeBoW (Pes1, Bop, WDR12) complex that plays a role in the processing of 28S and 5.8S ribosomal RNAs and the formation of the 60S ribosome. BOP1 contains seven WD repeats and was originally identified as a cDNA which inhibited cell proliferation. The deregulation of the BOP1 gene is proposed to contribute to colorectal tumorigenesis.

Gene ID: 23246

NCBI Accession: NP_056016

UniProt: Q14137