RAD50 antibody (AA 700-750)

Catalog No. ABIN7449388

This Rabbit Polyclonal antibody specifically detects RAD50 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for RAD50 antibody (AA 700-750) (ABIN7449388)

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD50 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RAD50 Antibody

Binding Specificity: AA 700-750

Purpose: Rabbit anti-Rad50 Antibody, Affinity Purified

Predicted Reactivity: Bovine,Dog,Rabbit,Orangutan,Monkey,Gorilla,Chimpanzee

Purification: Affinity Purified

Immunogen: between AA 700 and 750

Isotype: IgG

Application Details

Application Notes:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RAD50

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Alternative Name: Rad50

Background: Background: Rad50 is a component of the Mre11-Rad50-Nbs1 (MRN) complex that repairs DNA double strand breaks during DNA damage and homologous recombination and activates the S-phase checkpoint. Rad50 shows structural similarity to the structural maintenance of chromosomes (SMC) family of proteins. Rad50 has been shown to directly interact with BRCA2, TERF2IP, and ATM.

Gene ID: 10111

NCBI Accession: NP_005723

UniProt: Q92878

Pathways: DNA Damage Repair, Protein targeting to Nucleus