Recombinant CD56 antibody (AA 20-318)

Catalog No. ABIN7449431

The Rabbit Monoclonal anti-CD56 antibody has been validated for WB, IHC and ICC. It is suitable to detect CD56 in samples from Human.

Quick Overview for Recombinant CD56 antibody (AA 20-318) (ABIN7449431)

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD56 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: BLR152J

Product Details anti-CD56 Antibody

Binding Specificity: AA 20-318

Purpose: Rabbit anti-NCAM-1/CD56 Recombinant Monoclonal Antibody [BLR152J]

Immunogen: residues 20-318 (ECD)

Isotype: IgG

Application Details

Application Notes:

IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.

WB: 01:01,00

Restrictions: For Research Use only

Handling

Concentration: 100 μg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CD56

Target: CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))

Alternative Name: NCAM-1/CD56

Background: Background: NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].

Gene ID: 4684

NCBI Accession: NP_000606

UniProt: P13591