CRP antibody (Biotin)

Catalog No. ABIN7449517

This Goat Polyclonal antibody specifically detects CRP in WB, ELISA, IHC and ICC. It exhibits reactivity toward Human.

Quick Overview for CRP antibody (Biotin) (ABIN7449517)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CRP antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Product Details anti-CRP Antibody (Biotin)

Purpose: Goat anti-Human C-Reactive Protein (CRP) Antibody Biotinylated

Isotype: IgG

Application Details

Application Notes:

IHC: 1:250 - 1:2,500

ICC: 1:100 - 1:500

WB: 1:10,000 - 1:200,000

ELISA: 1:10,000 - 1:200,000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate Buffered Saline (PBS) containing 0.2 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Background: Background: The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 infection. [provided by RefSeq, Aug 2020]

Gene ID: 1401

UniProt: P02741

Pathways: Carbohydrate Homeostasis