CD45RO antibody
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- Target See all CD45RO products
- CD45RO
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD45RO antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Multiplex Immunofluorescence (mIF)
- Purpose
- Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]
- Immunogen
- Cultured T-cells from an IL-2-dependent T-cell line (CA1)
- Clone
- UCHL-1
- Isotype
- IgG
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anti-CD45RO (CD45RO) antibody
CD45RO Reactivity: Human, Mouse, Rat WB, IHC (p), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD45RO (CD45RO) antibodyGMP Grade CD45RO Reactivity: Human FACS, IHC, IP Host: Mouse Monoclonal UCHL1 unconjugated
anti-CD45RO (CD45RO) antibody (FITC)GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 FITC
anti-CD45RO (CD45RO) antibody (PE)GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 PE
anti-CD45RO (CD45RO) antibody (mFluor™450)GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 mFluor™450
anti-CD45RO (CD45RO) antibody (APC)GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 APC
anti-CD45RO (CD45RO) antibody (PE-CF®594)GMP Grade CD45RO Reactivity: Human FACS Host: Mouse Monoclonal UCHL1 PE-CF®594
anti-CD45RO (CD45RO) antibodyCD45RO Reactivity: Human, Chimpanzee, Marmoset FACS, IF, IHC (p) Host: Mouse Monoclonal UCHL-1 unconjugated
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- Application Notes
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IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
ICC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 05:10:00
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- Phosphate Buffered Saline (PBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Expiry Date
- 12 months
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- Target
- CD45RO
- Alternative Name
- CD45RO (CD45RO Products)
- Background
- Background: CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
- Gene ID
- 5788
- NCBI Accession
- NP_002829
- UniProt
- P08575
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