TSC1 antibody (C-Term)

Catalog No. ABIN7449615

This anti-TSC1 antibody is a Rabbit Polyclonal antibody detecting TSC1 in WB and IP. Suitable for Human and Mouse.

Quick Overview for TSC1 antibody (C-Term) (ABIN7449615)

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-TSC1 Antibody

Binding Specificity: C-Term

Purpose: Rabbit anti-TSC1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1100 and C-term

Isotype: IgG

Application Details

Application Notes:

IP: 1 - 5 μg/mg lysate

WB: 1:5,000 - 1:25,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TSC1

Target: TSC1 (Tuberous Sclerosis 1 (TSC1))

Alternative Name: TSC1

Background: Background: Tuberous sclerosis 1 protein (TSC1) forms a heterodimer with TSC2 to integrate cellular growth and stress signals. Defects in the TSC1 and TSC2 gene are responsible for the genetic disorder tuberous sclerosis. The TSC1/TSC2 complex functions in the mTOR pathway by negatively regulating mTOR activity via the small GTP-binding protein Rheb.

Gene ID: 7248

NCBI Accession: NP_000359

UniProt: Q92574

Pathways: RTK Signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation