PRKDC antibody (AA 2050-2100)
Quick Overview for PRKDC antibody (AA 2050-2100) (ABIN7449674)
Target
See all PRKDC AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 2050-2100
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Purpose
- Rabbit anti-DNA-PKcs Antibody, Affinity Purified
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Purification
- Affinity Purified
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Immunogen
- between AA 2050 and 2100
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Isotype
- IgG
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Application Notes
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IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:10,000
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Expiry Date
- 12 months
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- PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))
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Alternative Name
- DNA-PKcs
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Background
- Background: DNA-PKcs is the catalytic subunit of a DNA-dependent serine-threonine protein kinase (DNA-PK). DNA-PK is a heterotrimer comprised of DNA-PKcs and the Ku709/Ku86 dimer. DNA-PK is involved in DNA damage repair and V(D)J recombination. DNA-PK phosphorylates Artemis, a protein required for nonhomologous end-joining and is necessary for the loading of Artemis on damaged DNA.
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Gene ID
- 5591
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NCBI Accession
- NP_008835
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UniProt
- P78527
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Pathways
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
Target
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