UBE2K antibody (AA 150-200)

Catalog No. ABIN7449722

The Rabbit Polyclonal anti-UBE2K antibody is suitable to detect UBE2K in samples from Human and Mouse. It has been validated for WB and IP.

Quick Overview for UBE2K antibody (AA 150-200) (ABIN7449722)

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2K antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-UBE2K Antibody

Binding Specificity: AA 150-200

Purpose: Rabbit anti-E2-25K Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: Between AA 150 and 200

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for UBE2K

Target: UBE2K (Ubiquitin-Conjugating Enzyme E2K (UBE2K))

Alternative Name: E2-25K

Background: Background: Ubiquitin-conjugating enzyme E2-25 kDa (E2-25K) belongs to the ubiquitin-conjugating enzyme family. E2-25K interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation [taken from NCBI Entrez Gene (Gene ID: 3093)].

Gene ID: 3093

NCBI Accession: NP_005330

UniProt: P61086