EXOSC4 antibody (AA 1-50)

Catalog No. ABIN7449730

This Rabbit Polyclonal antibody specifically detects EXOSC4 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for EXOSC4 antibody (AA 1-50) (ABIN7449730)

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-EXOSC4 Antibody

Binding Specificity: AA 1-50

Purpose: Rabbit anti-EXOSC4 Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for EXOSC4

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Alternative Name: EXOSC4

Background: Background: Exosome component 4 (EXOSC4) is a non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm [taken from the Universal Protein Resource (UniProt) Q9NPD3].

Gene ID: 54512

NCBI Accession: NP_061910

UniProt: Q9NPD3