RNF31 antibody (AA 1022-1072)

Catalog No. ABIN7449808

This Rabbit Polyclonal antibody specifically detects RNF31 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for RNF31 antibody (AA 1022-1072) (ABIN7449808)

Target: RNF31 (Ring Finger Protein 31 (RNF31))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF31 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RNF31 Antibody

Binding Specificity: AA 1022-1072

Purpose: Rabbit anti-RNF31 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 1022 and 1072

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for RNF31

Target: RNF31 (Ring Finger Protein 31 (RNF31))

Alternative Name: RNF31

Background: Background: RING finger protein 31 is an E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear polyubiquitin chains in a head-to-tail manner to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways [taken from the Universal Protein Resource (UniProt) Q96EP0].

Gene ID: 55072

NCBI Accession: NP_060469

UniProt: Q96EP0