ATG13 antibody (AA 450-500)

Catalog No. ABIN7449999

This anti-ATG13 antibody is a Rabbit Polyclonal antibody detecting ATG13 in WB and IP. Suitable for Human and Mouse.

Quick Overview for ATG13 antibody (AA 450-500) (ABIN7449999)

Target: ATG13 (Autophagy Related 13 (ATG13))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG13 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-ATG13 Antibody

Binding Specificity: AA 450-500

Purpose: Rabbit anti-ATG13/KIAA0652 Antibody, Affinity Purified

Predicted Reactivity: X. tropicalis,Bovine,Orangutan,Chimpanzee

Purification: Affinity Purified

Immunogen: Between AA 450 and 500

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ATG13

Target: ATG13 (Autophagy Related 13 (ATG13))

Alternative Name: ATG13/KIAA0652

Background: Background: Autophagy-related protein 13 (ATG13) is an autophagy factor required for autophagosome formation and mitophagy. It is a target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, ATG13 plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation [taken from the Universal Protein Resource (UniProt) O75143].

Gene ID: 9776

UniProt: O75143

Pathways: PI3K-Akt Signaling, Autophagy