CENPI antibody (AA 50-100)

Catalog No. ABIN7450103

The Rabbit Polyclonal anti-CENPI antibody has been validated for WB and IP. It is suitable to detect CENPI in samples from Human.

Quick Overview for CENPI antibody (AA 50-100) (ABIN7450103)

Target: CENPI (Centromere Protein I (CENPI))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPI antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-CENPI Antibody

Binding Specificity: AA 50-100

Purpose: Rabbit anti-CENP-I Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 50 and 100

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for CENPI

Target: CENPI (Centromere Protein I (CENPI))

Alternative Name: CENP-I

Background: Background: Centromere protein I (CENP-I) is a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. CENP-I may be involved in incorporation of newly synthesized CENP-A into centromeres via its interaction with the CENPA-NAC complex. CENP-I is required for the localization of CENP-F, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. CENP-A is involved in the response of gonadal tissues to follicle-stimulating hormone [taken from the Universal Protein Resource (UniProt) Q92674].

Gene ID: 2491

NCBI Accession: NP_006724

UniProt: Q92674