DYNC1H1 antibody (AA 1250-1300)

Catalog No. ABIN7450192

This Rabbit Polyclonal antibody specifically detects DYNC1H1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for DYNC1H1 antibody (AA 1250-1300) (ABIN7450192)

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1H1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DYNC1H1 Antibody

Binding Specificity: AA 1250-1300

Purpose: Rabbit anti-DYNC1H1 Antibody, Affinity Purified

Predicted Reactivity: Rat

Purification: Affinity Purified

Immunogen: Between AA 1250 and 1300

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DYNC1H1

Target: DYNC1H1 (Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1))

Alternative Name: DYNC1H1

Background: Background: Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains. DYNC1H1 is a member of the cytoplasmic dynein heavy chain family [taken from NCBI Entrez Gene (Gene ID: 1778)].

Gene ID: 1778

NCBI Accession: NP_001367

UniProt: Q14204

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization