ESCO2 antibody (AA 200-250)

Catalog No. ABIN7450220

The Rabbit Polyclonal anti-ESCO2 antibody has been validated for WB and IP. It is suitable to detect ESCO2 in samples from Human.

Quick Overview for ESCO2 antibody (AA 200-250) (ABIN7450220)

Target: ESCO2 (Establishment of Cohesion 1 Homolog 2 (ESCO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESCO2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-ESCO2 Antibody

Binding Specificity: AA 200-250

Purpose: Rabbit anti-ESCO2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: between AA 200 and 250

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ESCO2

Target: ESCO2 (Establishment of Cohesion 1 Homolog 2 (ESCO2))

Alternative Name: ESCO2

Background: Background: ESCO2 (establishment of cohesion 1 homolog2) is an acetyltransferase that is essential to sister chromatid cohesion during S phase. Recent studies reveal that ESCO2 associates with components of the CoREST transcriptional repression complex. ESCO2 has also been shown to possess histone H3 K9 methylation activity. These findings suggest a role for ESCO2 in transcriptional regulation via the modulation of chromatin structure.

Gene ID: 157570

NCBI Accession: NP_001017420

UniProt: Q56NI9

Pathways: Positive Regulation of Endopeptidase Activity