FDFT1 antibody (AA 367-417)

Catalog No. ABIN7450244

The Rabbit Polyclonal anti-FDFT1 antibody has been validated for WB and IP. It is suitable to detect FDFT1 in samples from Human.

Quick Overview for FDFT1 antibody (AA 367-417) (ABIN7450244)

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FDFT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FDFT1 Antibody

Binding Specificity: AA 367-417

Purpose: Rabbit anti-FDFT1 Antibody, Affinity Purified

Predicted Reactivity: Bovine,Orangutan

Purification: Affinity Purified

Immunogen: Between AA 367 and 417

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FDFT1

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Alternative Name: FDFT1

Background: Background: Farnesyl-diphosphate farnesyltransferase 1 (FDFT1) is a membrane-associated enzyme located at a branch point in the mevalonate pathway. FDFT1 is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene [taken from NCBI Entrez Gene (Gene ID: 2222)].

Gene ID: 2222

UniProt: P37268

Pathways: Regulation of Lipid Metabolism by PPARalpha