FMR1 antibody (AA 582-632)

Catalog No. ABIN7450257

This anti-FMR1 antibody is a Rabbit Polyclonal antibody detecting FMR1 in WB and IP. Suitable for Human and Mouse.

Quick Overview for FMR1 antibody (AA 582-632) (ABIN7450257)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FMR1 Antibody

Binding Specificity: AA 582-632

Purpose: Rabbit anti-FMR1/FMRP Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 582 and 632

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Alternative Name: FMR1/FMRP

Background: Background: Fragile X mental retardation protein 1 is the product of the gene FMR1, also known as FMRP. This protein binds RNA and is associated with polysomes. FMRP may also be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1).

Gene ID: 2332

UniProt: Q06787, Q86787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development