FOXA1 antibody (AA 422-472)

Catalog No. ABIN7450258

This Rabbit Polyclonal antibody specifically detects FOXA1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for FOXA1 antibody (AA 422-472) (ABIN7450258)

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-FOXA1 Antibody

Binding Specificity: AA 422-472

Purpose: Rabbit anti-FOXA1/HNF3A Antibody, Affinity Purified

Predicted Reactivity: Rat,X. laevis,X. tropicalis

Purification: Affinity Purified

Immunogen: Between AA 422 and 472

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for FOXA1

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Alternative Name: FOXA1/HNF3A

Background: Background: Forkhead box protein A1 (FOXA1) is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver [taken from NCBI Entrez Gene (Gene ID: 3169)].

Gene ID: 3169

UniProt: P55317

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis