Glycogen Synthase 1 antibody (AA 625-675)

Catalog No. ABIN7450309

This Rabbit Polyclonal antibody specifically detects Glycogen Synthase 1 in WB and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for Glycogen Synthase 1 antibody (AA 625-675) (ABIN7450309)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycogen Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-Glycogen Synthase 1 Antibody

Binding Specificity: AA 625-675

Purpose: Rabbit anti-GYS1 Antibody, Affinity Purified

Predicted Reactivity: Orangutan

Purification: Affinity Purified

Immunogen: Between AA 625 and 675

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Alternative Name: GYS1

Background: Background: Glycogen synthase 1 (muscle) (GYS1) catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in the GYS1 gene are associated with muscle glycogen storage disease [taken from NCBI Entrez Gene (Gene ID: 2997)].

Gene ID: 2997

NCBI Accession: NP_002094

UniProt: P13807

Pathways: PI3K-Akt Signaling, AMPK Signaling, Cellular Glucan Metabolic Process